Publications

2026

  1. LEIA: Learned Environment for Interactive Architected Materials
    Haiqian Yang, Yuan Cao, and Markus J. Buehler
    2026
    DOI
  2. Nature Methods
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    MultiCell: geometric learning in multicellular development
    Haiqian Yang, George Roy, Anh Q Nguyen, Dapeng Bi, Tomer Stern, Markus J Buehler, and Ming Guo
    Nature Methods, 2026
    DOI Code
  3. Collective transitions from orbiting to matrix invasion in three-dimensional multicellular spheroids
    Jiwon Kim, Hyuntae Jeong, Carles Falcó, Alex M Hruska, W Duncan Martinson, Alejandro Marzoratti, Mauricio Araiza, Haiqian Yang, Vera C Fonseca, Stephen A Adam, and  others
    Nature Physics, 2026
  4. Unified Transcriptome and Mechanics Map of the Intact Mammalian Preimplantation Embryo In Situ
    Ehsan Habibi*, Anubhav Sinha*, Haiqian Yang*, Payman Yadollahpour*, Yiwei Li, Lani Lee, David A Wollensak, Zachary D Chiang, Denny Sakkas, Edward S Boyden, and  others
    bioRxiv, 2026
    *These authors contributed equally.

2025

  1. NeurIPS ML4PS
    Learning Drosophila ventral furrow formation with graph neural networks
    Shaoxun Huang, Haiqian Yang, Hyuntae Jeong, Xinran O Zhao, Ian Y Wong, Markus J Buehler, Adam C Martin, and Ming Guo
    NeurIPS Machine Learning and the Physical Sciences Workshop, 2025
  2. arXiv
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    Orientational ordering in active nematic solids
    Haiqian Yang, Ming Guo, and L. Mahadevan
    arXiv, 2025
    DOI

2024

  1. PRX Life
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    Learning collective cell migratory dynamics from a static snapshot with graph neural networks
    Haiqian Yang, Florian Meyer, Shaoxun Huang, Liu Yang, Cristiana Lungu, Monilola A Olayioye, Markus J Buehler, and Ming Guo
    PRX Life, 2024
    DOI Code
  2. JMPS
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    An interpenetrating-network theory of the cytoskeletal networks in living cells
    Haiqian Yang, Thomas Henzel, Eric M Stewart, and Ming Guo
    Journal of the Mechanics and Physics of Solids, 2024
    DOI Code
  3. PRR
    Nonlinear mechanosensation in fiber networks
    Estelle Berthier, Haiqian Yang, Ming Guo, Pierre Ronceray, and Chase P Broedersz
    Physical Review Research, 2024
  4. Commun. Biol.
    Vimentin is a key regulator of cell mechanosensing through opposite actions on actomyosin and microtubule networks
    Farid Alisafaei, Kalpana Mandal, Renita Saldanha, Maxx Swoger, Haiqian Yang, Xuechen Shi, Ming Guo, Heidi Hehnly, Carlos A Castañeda, Paul A Janmey, Alison E Patteson, and Vivek B Shenoy
    Communications Biology, 2024
  5. Commun. Biol.
    Repeat DNA methylation is modulated by adherens junction signaling
    Lisa-Marie Brenner, Florian Meyer, Haiqian Yang, Anja R Köhler, Pavel Bashtrykov, Ming Guo, Albert Jeltsch, Cristiana Lungu, and Monilola A Olayioye
    Communications Biology, 2024

2023

  1. PNAS
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    Local response and emerging nonlinear elastic length scale in biopolymer matrices
    Haiqian Yang, Estelle Berthier, Chenghai Li, Pierre Ronceray, Yu Long Han, Chase P Broedersz, Shengqiang Cai, and Ming Guo
    Proceedings of the National Academy of Sciences, 2023
    DOI
  2. Book Chapter
    Mechanobiology of collective cell migration in 3D microenvironments
    Alex M Hruska, Haiqian Yang, Susan E Leggett, Ming Guo, and Ian Y Wong
    In Engineering and Physical Approaches to Cancer, 2023

2022

  1. Front. Cell. Dev. Biol.
    Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells
    Suganya Sivagurunathan, Amir Vahabikashi, Haiqian Yang, Jun Zhang, Kelly Vazquez, Dhivyaa Rajasundaram, Yuliya Politanska, Hiam Abdala-Valencia, Jacob Notbohm, Ming Guo, Stephen A Adam, and Robert D Goldman
    Frontiers in cell and developmental biology, 2022
  2. Nature Physics
    Collective curvature sensing and fluidity in three-dimensional multicellular systems
    Wenhui Tang, Amit Das, Adrian F Pegoraro, Yu Long Han, Jessie Huang, David A Roberts, Haiqian Yang, Jeffrey J Fredberg, Darrell N Kotton, Dapeng Bi, and Ming Guo
    Nature Physics, 2022

2021

  1. PNAS
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    Configurational fingerprints of multicellular living systems
    Haiqian Yang, Adrian F Pegoraro, Yulong Han, Wenhui Tang, Rohan Abeyaratne, Dapeng Bi, and Ming Guo
    Proceedings of the National Academy of Sciences, 2021
    DOI Code